A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
胶质母细胞瘤
抗原
癌症研究
医学
免疫学
作者
Donald M. O’Rourke,MacLean P. Nasrallah,Arati Desai,J. Joseph Melenhorst,Keith G. Mansfield,Jennifer J.D. Morrissette,Maria Martinez‐Lage,Steven Brem,Eileen Maloney,Angela Shen,Randi Isaacs,Suyash Mohan,Gabriela Plesa,Simon F. Lacey,Jean‐Marc Navenot,Zhaohui Zheng,Bruce L. Levine,Hideho Okada,Carl H. June,Jennifer L. Brogdon,Marcela V. Maus
出处
期刊:Science Translational Medicine [American Association for the Advancement of Science (AAAS)] 日期:2017-07-19卷期号:9 (399)被引量:1382