Can lung ultrasound differentiate between bacterial and viral pneumonia in children?

医学 肺炎 金标准(测试) 胸片 病毒性肺炎 预测值 肺超声 内科学 细菌性肺炎 试验预测值 前瞻性队列研究 正谓词值 胃肠病学 2019年冠状病毒病(COVID-19) 疾病 传染病(医学专业)
作者
Deepawali Malla,Vinita Rathi,Sunil Gomber,Lalendra Upreti
出处
期刊:Journal of Clinical Ultrasound [Wiley]
卷期号:49 (2): 91-100 被引量:18
标识
DOI:10.1002/jcu.22951
摘要

Abstract Purpose This study evaluates whether LUS can differentiate between bacterial and viral pneumonia in children and thus affect their management. Methods The prospective, cross‐sectional, analytical study included 200 children under 12 years of age (excluding neonates) with clinical suspicion of pneumonia who had undergone a chest radiograph (CR). The CR and LUS findings were classified as bacterial or viral pneumonia. The final diagnosis was made on the basis of a combination of clinical profile, available routine laboratory investigations and CR diagnosis which was taken as the gold standard for the study and LUS was compared with the gold standard. Results LUS has a high sensitivity (91%; 95% CI [84‐96]) and specificity (91.3%; 95% CI [84‐96]) in diagnosing bacterial pneumonia with a high positive predictive value (91.9%; 95% CI [85‐96]) and negative predictive value (90.3%; 95% CI [82‐95]). For diagnosing viral pneumonia, the sensitivity of LUS was 78.4%; (95% CI [68‐86]), specificity was high (90.4%; 95% CI [83‐95]) and so was the positive predictive value (87.3%; 95% CI [78‐94]) and negative predictive value (91.3%; 95% CI [84‐96]). Conclusion LUS has a high accuracy in differentiating between bacterial and viral pneumonia in children and can help in their management by avoiding an ill‐advised use of antibiotic therapy.
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