Electrochemical sensing of adrenaline using surface modified carbon nanotube paste electrode

A new interesting insight into the construction of a voltammetric sensor for the detection of Adrenaline (AD) has been presented. Poly oxalic acid modified carbon nanotube paste electrode (POXMCNTPE) exhibited the boosted detecting ability towards the AD compared to the bare CNTPE (BCNTPE) as a sensing device. The detection of AD (pH 6.5) has been executed through the cyclic voltammetry (CV) and differential pulse voltammetry (DPV) approaches. The surface morphological features, elemental analysis and electrochemical properties of the proposed electrode are revealed by Field emission scanning electron microscopy (FE-SEM), Energy dispersive X-ray spectroscopy (EDS), Electrochemical impedance spectroscopy (EIS), and CV technique. The number of electropolymerisation cycles were optimized. The few factors influencing the voltammetric signal of AD, such as the impact of pH and the effect of scan rate were examined. The detection limit (DL) 3.1 × 10−8 M and quantification limit (QL) 1.0 × 10−7 M was gained from the proposed method. The designed sensor displayed the superb selectivity, good reproducibility, repeatability and an excellent antifouling property. Hence, the proposed procedure was effectively implemented to detect the AD in the injection sample and as well as in the blood serum sample. The accomplished outcome from the proposed electrode reveals that it is a favourable candidate for electrochemical sensing of AD.