医学
小关节
变性(医学)
腰椎
关节突关节
面(心理学)
解剖
骨关节炎
关节病
椎间盘
退行性疾病
腰椎
尸体痉挛
外科
口腔正畸科
椎间盘
病理
中枢神经系统疾病
人格
替代医学
五大性格特征
社会心理学
心理学
作者
Robert J. Moore,Tania Crotti,Orso L. Osti,Robert D. Fraser,B. Vernon‐Roberts
出处
期刊:Spine
[Ovid Technologies (Wolters Kluwer)]
日期:1999-03-01
卷期号:24 (6): 519-525
被引量:83
标识
DOI:10.1097/00007632-199903150-00003
摘要
Facet joints from sheep lumbar spines were examined for histologic evidence of osteoarthrosis after anular incision.To describe the sequence of changes in facet joints in an animal model of disc degeneration.There are many studies with results showing a link between facet joint osteoarthrosis and disc degeneration, but the development of osteoarthrosis in facet joints has not been observed in a controlled study of disc degeneration.Histologic features of facet joint degeneration were compared with established descriptions of human osteoarthrosis, and the sequence of changes was documented in a controlled prospective study of disc degeneration.Osteoarthrosis in sheep lumbar facet joints is similar to that described in human joints and develops in response to anular injury. Discs degenerate relatively soon after anular incision, but there is a long delay in the appearance of significant changes to the facet joints at the level of anular incision and adjacent levels.The results shows that facet joints in sheep undergo osteoarthrotic changes in response to disc degeneration and confirm the sheep as a suitable model for the study of degenerative spinal disorders.
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