自愈水凝胶
蛋白质工程
组织工程
纳米技术
材料科学
计算机科学
生化工程
生物医学工程
化学
工程类
生物化学
酶
高分子化学
作者
Niyousha Davari,Negar Bakhtiary,Mehran Khajehmohammadi,Soulmaz Sarkari,Hamidreza Tolabi,Farnaz Ghorbani,Behafarid Ghalandari
出处
期刊:Polymers
[MDPI AG]
日期:2022-02-28
卷期号:14 (5): 986-986
被引量:40
标识
DOI:10.3390/polym14050986
摘要
The successful design of a hydrogel for tissue engineering requires a profound understanding of its constituents' structural and molecular properties, as well as the proper selection of components. If the engineered processes are in line with the procedures that natural materials undergo to achieve the best network structure necessary for the formation of the hydrogel with desired properties, the failure rate of tissue engineering projects will be significantly reduced. In this review, we examine the behavior of proteins as an essential and effective component of hydrogels, and describe the factors that can enhance the protein-based hydrogels' structure. Furthermore, we outline the fabrication route of protein-based hydrogels from protein microstructure and the selection of appropriate materials according to recent research to growth factors, crucial members of the protein family, and their delivery approaches. Finally, the unmet needs and current challenges in developing the ideal biomaterials for protein-based hydrogels are discussed, and emerging strategies in this area are highlighted.
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