Electrochemical detection of dopamine by using nickel supported carbon nanofibers modified screen printed electrode

The detection of the neurotransmitter dopamine in medicinal and human biological samples has attracted the huge interest of researchers in recent years. Carbon nanofiber is a potential nanocarbon material for the detection of dopamine (DA) due to its good electrochemical properties. In this work, carbon nanofiber (CNF) supported nickel nanoparticles ([email protected]) were prepared by wet impregnation method and characterized by TEM, EDS, XRD and FTIR analysis. The [email protected] modified screen printed electrode gave superior electrochemical response. Moreover, the [email protected]/CNF shows a broad linear detection range (0.1-10 μM), a low detection limit (0.03 μM) by using DPV analysis and excellent selectivity. The developed electrode shows good reproducibility, stability, and repeatability. The [email protected]/SPCE has been also utilized for the detection of DA in pharmaceutical, human blood serum and urine samples with substantial recovery outcomes. Therefore, the prepared [email protected]/SPCE will be a capable platform for the electrochemical detection of DA in biological or medicinal samples.