医学
剪裁(形态学)
血管内卷取
蛛网膜下腔出血
动脉瘤
优势比
外科
随机对照试验
临床试验
置信区间
栓塞
大脑中动脉
血管内治疗
放射科
内科学
缺血
哲学
语言学
出处
期刊:PubMed
日期:2023-03-01
卷期号:51 (2): 230-238
被引量:1
标识
DOI:10.11477/mf.1436204739
摘要
Selection of a reliable method to offer prompt treatment and prevent rebleeding of ruptured cerebral aneurysms is necessary because rebleeding can worsen patient outcomes. Surgical interventions for ruptured cerebral aneurysms have evolved from cervical artery ligation to clipping using a surgical microscope and endovascular coil embolization. In the International Subarachnoid Aneurysm Trial, a multicenter randomized controlled trial, the incidence of poor outcomes at 1 year after treatment was 23.7% and 30.6% in the endovascular coiling and neurosurgical clipping groups, respectively, which demonstrated the superiority of endovascular coiling over neurosurgical clipping(p = 0.0019)in patients with ruptured intracranial aneurysms. Rates of survival and independence in activities of daily living at 10 years after treatment were higher in the coiling group than in the clipping group(odds ratio: 1.34; 95% confidence interval: 1.07-1.67). The Barrow Ruptured Aneurysm Trial and several meta-analyses yielded similar results, showing the superiority of endovascular coiling over neurosurgical clipping with respect to short- and long-term clinical outcomes in patients. These results have also been reflected in the guidelines. Large clinical trials have analyzed and compared the effects of these treatments. In addition, the subsequent decade has witnessed remarkable advances in medical devices and treatment techniques for cerebral aneurysms. Clinical findings and cerebral aneurysm characteristics should be carefully evaluated to select the optimal treatment strategy for patients with ruptured cerebral aneurysms.
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