转移RNA
生物
铜绿假单胞菌
毒力
翻译(生物学)
核糖核酸
遗传学
功能(生物学)
计算生物学
细菌
基因
信使核糖核酸
作者
Mariana D. Mandler,Siddhardha S. Maligireddy,Wilfried M. Guiblet,Christina M. Fitzsimmons,Kayla S. McDonald,Delayna L. Warrell,Pedro J. Batista
出处
期刊:RNA
日期:2024-04-29
卷期号:: rna.080004.124-rna.080004.124
标识
DOI:10.1261/rna.080004.124
摘要
RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria, tRNA modifications are crucial for responding to stress and regulating the expression of virulence factors. Although tRNA modifications are well-characterized in a few model organisms, our knowledge of tRNA modifications in human pathogens, such as
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