The purpose of this study is to investigate the relationship between entrepreneurial motivation, entrepreneurial attitude and entrepreneurial intention among students from science and technology college who have taken innovation and entrepreneurship courses and to determine whether or not entrepreneurial attitude influences the relationship between entrepreneurial motivation and entrepreneurial intention. Research findings: Entrepreneurial motivation influences entrepreneurial attitude and entrepreneurial intention, entrepreneurial attitude has a significant effect on entrepreneurial intention and entrepreneurial attitude has a complete mediating effect on the relationship between entrepreneurial motivation and entrepreneurial intention. In other words, in order for entrepreneurial education to enhance students' entrepreneurial intention, it is far more effective to enhance students' entrepreneurial attitudes compared to enhancing their entrepreneurial motivation. It is recommended that entrepreneurial education in schools can be achieved by acquiring entrepreneurship knowledge, providing students with a support system, participating in entrepreneurship internship activities, hearing stories of entrepreneurial failures or seeking professional advice, writing entrepreneurship plans, participating in innovative entrepreneurship activities or competitions and establishing good interpersonal relationships, etc. to enhance students' entrepreneurial attitude.