Application of Nanocellulose for Wound Dressings

Chapter 8 Application of Nanocellulose for Wound Dressings B.A. Aderibigbe, B.A. Aderibigbe Department of Chemistry, University of Fort Hare, Alice Campus, Eastern Cape, South AfricaSearch for more papers by this author B.A. Aderibigbe, B.A. Aderibigbe Department of Chemistry, University of Fort Hare, Alice Campus, Eastern Cape, South AfricaSearch for more papers by this author Book Editor(s):Mainak Mukhopadhyay, Mainak Mukhopadhyay Department of Bioscience, JIS University, West Bengal, IndiaSearch for more papers by this authorDebalina Bhattacharya, Debalina Bhattacharya Department of Microbiology, Maulana Azad College, Kolkata, IndiaSearch for more papers by this author First published: 06 February 2024 https://doi.org/10.1002/9781394172825.ch8 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onEmailFacebookTwitterLinkedInRedditWechat Summary Nanocellulose-based biomedical materials offer distinct properties, such as excellent biocompatibility, reduced cytotoxic effects, biodegradability, and good mechanical properties. It is affordable and readily available, making it a sustainable biomaterial for biomedical applications. One of the outstanding biomedical applications of cellulose-based materials is in the design of wound dressings. Wound healing is very complex and using an appropriate wound dressing is crucial to afford accelerated healing with reduced scar formation. There are several commercially available wound dressings; however, some of them are not biocompatible and do not promote an accelerated wound-healing process. Nanocellulose-based wound dressings exhibit excellent features that are useful for the treatment of chronic, infected, high exuding and bleeding wounds. The surfaces of nanocellulose-based biomaterials have been modified with bioactive molecules for improved cellular adhesion, proliferation, and differentiation processes that are useful in skin regeneration. Different forms of wound dressings have been prepared from nanocellulose-based biomaterials. However, the development of nanocellulose-based wound dressings is still in its infancy. There have been reports ( in vitro and in vivo ) on the efficacy of nanocellulose-based dressings for the treatment of bleeding, exuding, chronic, acute wounds, and skin regeneration. This chapter will give a comprehensive report on the different forms of nanocellulose-based wound dressings and future perspectives. References Santos , D. , Silva , U.F. , Duarte , F.A. , Bizzi , C.A. , Flores , E.M. , Mello , P.A. , Ultrasound-assisted acid hydrolysis of cellulose to chemical building blocks: Application to furfural synthesis . Ultrason. 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