蛋白尿
肾功能
医学
肾脏疾病
肌酐
逻辑回归
内科学
全国健康与营养检查调查
体质指数
胃肠病学
环境卫生
人口
作者
Shifang Qu,Jiaxin Fang,Saisai Zhao,Yuxiang Wang,Wenhui Gao,Zhiyao Li,Xu Han,Yuan Zhang,Shunyao Shi,Xiaowei Cheng,Zhigang Liu,Lina Jin,Yan Yao
标识
DOI:10.1016/j.numecd.2023.11.006
摘要
Abstract
Background and Aims
Chronic Kidney Disease (CKD) is characterized by a high inflammation status with ever-increasing prevalence, and defined as low estimated glomerular filtration rate (eGFR) or albuminuria. Both low eGFR and albuminuria can have independent effects on the body. The dietary inflammatory index (DII) is a validated tool used to assess the inflammatory potential of the diet. We aim to explore not only the association between DII and CKD, but also the associations of DII with low eGFR and albuminuria, respectively. In addition, their associations in different subgroups remain to be explored. Methods and Results
18,070 participants from the 2011-2018 NHANES with complete data of dietary intake and laboratory data were involved in our study. The data of 24-hour dietary recall interview was used to calculate DII, CKD could be reflected by laboratory data of creatinine and albumin. Then weighted multivariate logistic regression models and subgroup analyses were performed. The prevalence of low eGFR, albuminuria and CKD were 6.8%, 9.8% and 14.5%, respectively. A positive association between DII and low eGFR was observed (OR=1.12, 95%CI: 1.05-1.21), Q2, Q3 and Q4 are positively associated with a significant 39%, 65% and 71% increased risk of low eGFR compared with Q1 (P for trend<0.05). DII was also associated with CKD (OR=1.06, 95%CI: 1.01-1.11). Conclusion
Significant positive associations of DII with CKD and low eGFR were observed. But we didn't find such association between DII and albuminuria.
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