氧化应激
活性氧
癌细胞
抗氧化剂
癌症
DNA损伤
氧化磷酸化
癌症研究
细胞生物学
化学
生物
生物化学
DNA
遗传学
作者
Ebraheem Abdu Musad Saleh,F Al-Dolaimy,Yasir Q. Аlmajidi,Sayfiddin Baymakov,Mohammed Abdul Kader,Muhammad Ikram Ullah,Ahmed Abbas,Ibrahim Hammoud Khlewee,Yashwant Singh Bisht,Ali Alsaalamy
标识
DOI:10.1016/j.prp.2023.154664
摘要
Oxidative stress is a physiological condition that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the cell's antioxidant defense system. ROS are highly reactive molecules that can cause damage to cellular structures such as DNA, proteins, and lipids. the regulation of ROS levels and the antioxidant defense system is crucial for cancer prevention and treatment. Strategies to enhance antioxidant defenses or induce oxidative stress selectively in cancer cells are being developed as potential therapeutic approaches. targeting oxidative stress in cancer treatment is an active area of research with several potential therapeutic approaches being investigated. Developing selective and effective therapies that target oxidative stress in cancer cells while sparing normal cells will be crucial for improving cancer treatment outcomes.
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