化学
丙烯酰氯
基础(拓扑)
催化作用
铵
水溶液
药物化学
有机化学
丙烯酸酯
共聚物
数学分析
数学
聚合物
作者
Jizhou Song,Takeru Torigoe,Yoichiro Kuninobu
标识
DOI:10.1002/ejoc.202301015
摘要
Abstract The 5‐ammonium‐4,4‐dimethylvaleryl (Amv) group was generated by conversion of acryloyl group through decatungstate‐catalyzed addition of C(sp 3 )−H bond of i ‐BuNH 2 ⋅HCl under the irradiation of UV light (365 nm or 405 nm). Treatment of Amv‐protected alcohols and anilines with aqueous Na 2 CO 3 promoted the efficient deprotection of Amv. This is a unique method for the efficient removal of acryloyl groups from phenols, alcohols, and anilines. The selective removal of acryloyl groups through Amv in the presence of another acetyl or benzoyl group was demonstrated. The base‐triggered intramolecular cyclization of Amv was monitored by the release of a fluorescent molecule, and it was found that cyclization by Na 2 CO 3 was very rapid (within 1 min) and that some weak bases such as 2,6‐lutidine are sufficient to promote cyclization.
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