口腔给药
医学
癌症疼痛
美沙酮
突破性疼痛
颊粘膜
药代动力学
癌症
麻醉
牙科
内科学
口腔
作者
Laura Kirkham,Jennie Pickard,Alison Phippen,Sarah Clelland,Samantha Kay,Lesley A. Henson
标识
DOI：10.1016/j.jpainsymman.2023.08.003
摘要
This case report describes the effective use of buccal methadone for a patient with severe cancer pain and impaired oral absorption secondary to metastatic bowel obstruction. The pharmacokinetics required for buccal administration of opioids alongside key practical prescribing considerations are discussed.
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