Correlation of shear-wave elastography parameters with the molecular subtype and axillary lymph node status in breast cancer

医学 乳腺癌 弹性成像 淋巴结 转移 超声波 放射科 病理 癌症 核医学 肿瘤科 内科学
作者
Hee Jeong Kim,Hak Hee Kim,Woo Jung Choi,Eun Young Chae,Hee Jung Shin,Joo Hee
出处
期刊:Clinical Imaging [Elsevier BV]
卷期号:101: 190-199 被引量:3
标识
DOI:10.1016/j.clinimag.2023.06.006
摘要

To examine correlations between shear-wave elastography (SWE) parameters with molecular subtype and axillary lymph node (LN) status of breast cancer.We retrospectively analyzed 545 consecutive women (mean age, 52.7 ± 10.7 years; range, 26-83) with breast cancer who underwent preoperative breast ultrasound with SWE between December 2019 and January 2021. SWE parameters (Emax, Emean, and Eratio) and the histopathologic information from surgical specimens including histologic type, histologic grade, size of invasive cancer, hormone receptor and HER2 status, Ki-67 proliferation index, and axillary LN status were analyzed. The relationships between SWE parameters and histopathologic findings were analyzed using an independent sample t-test, one-way ANOVA test with Tukey's post hoc test, and logistic regression analyses.Higher stiffness values of SWE were associated with larger lesion size (>20 mm) on ultrasound, high histologic grade, larger invasive cancer size (>20 mm), high Ki-67, and axillary LN metastasis. Emax and Emean were the lowest in the luminal A-like subtype, and all three parameters were the highest in the triple-negative subtype. Lower value of Emax was independently associated with the luminal A-like subtype (P = 0.04). Higher value of Emean was independently associated with axillary LN metastasis for tumors ≤ 20 mm (P = 0.03).Increases in the tumor stiffness values on SWE were significantly associated with aggressive histopathologic features of breast cancer. Lower stiffness values were associated with the luminal A-like subtype, and tumors with higher stiffness values were associated with axillary LN metastasis in small breast cancers.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
吕布完成签到,获得积分10
刚刚
chwjx发布了新的文献求助10
1秒前
1秒前
MHCL完成签到 ,获得积分10
1秒前
RayLam完成签到,获得积分10
1秒前
1762120完成签到,获得积分10
1秒前
季风气候完成签到 ,获得积分10
2秒前
Li完成签到,获得积分10
2秒前
rhq完成签到,获得积分10
3秒前
共享精神应助焓晓芈采纳,获得10
4秒前
电催化CYY完成签到,获得积分10
4秒前
独特的易形完成签到,获得积分10
4秒前
清脆晓曼完成签到,获得积分10
5秒前
好好好完成签到 ,获得积分10
5秒前
咩咩完成签到,获得积分10
5秒前
一人完成签到,获得积分10
5秒前
清脆的飞丹完成签到,获得积分10
6秒前
曙光完成签到,获得积分10
6秒前
jxcandice完成签到,获得积分10
6秒前
范月月完成签到 ,获得积分10
6秒前
小飞棍完成签到,获得积分10
7秒前
心想事陈完成签到,获得积分10
7秒前
liu完成签到,获得积分10
7秒前
花已烬完成签到,获得积分10
7秒前
miracle完成签到 ,获得积分10
8秒前
Iris完成签到 ,获得积分10
8秒前
易寒完成签到,获得积分10
9秒前
小石头完成签到,获得积分10
9秒前
小范要努力完成签到,获得积分10
9秒前
fx完成签到,获得积分10
11秒前
kaka完成签到,获得积分10
11秒前
喜悦的向日葵完成签到,获得积分10
12秒前
Ted完成签到,获得积分10
12秒前
dtcao完成签到,获得积分10
13秒前
Crystal完成签到 ,获得积分10
13秒前
吉祥高趙完成签到 ,获得积分10
14秒前
阳光绿柏完成签到,获得积分10
14秒前
zy3637完成签到 ,获得积分10
15秒前
王先生完成签到,获得积分10
15秒前
FB完成签到,获得积分10
16秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968603
求助须知:如何正确求助?哪些是违规求助? 3513420
关于积分的说明 11168029
捐赠科研通 3248900
什么是DOI,文献DOI怎么找? 1794540
邀请新用户注册赠送积分活动 875187
科研通“疑难数据库(出版商)”最低求助积分说明 804676