医学
间质性肺病
特发性肺纤维化
免疫学
CD14型
类风湿性关节炎
发病机制
肺纤维化
纤维化
肺
内科学
免疫系统
作者
Jill A. Poole,Aaron D. Schwab,Geoffrey M. Thiele,Bryant R. England,Amy Nelson,Angela Gleason,Michael J. Duryee,Kristina L. Bailey,Debra J. Romberger,Daniel Hershberger,Joel Van De Graaff,Sara M. May,Rhonda Walenz,Bridget Kramer,Ted R. Mikuls
标识
DOI:10.1093/rheumatology/keae572
摘要
Though interstitial lung disease (ILD) contributes to excess morbidity and mortality in rheumatoid arthritis (RA), RA-ILD pathogenesis remains incompletely defined. As intermediate, non-classical and suppressed CD14+ monocytes are expanded in RA-ILD, this study sought to characterize gene expression profiles of circulating monocytes in RA-ILD.
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