鉴别诊断
甲基化
医学
病理
DNA甲基化
差速器(机械装置)
计算生物学
生物信息学
生物
物理
遗传学
基因
热力学
基因表达
作者
Meng Yang,Huansha Yu,Hongxiang Feng,Jianghui Duan,Kaige Wang,Bing Tong,Yunzhi Zhang,Wei Li,Yu Wang,Chaoyang Liang,Hongliang Sun,Dingrong Zhong,Li Wang,Chen Huang,Chengxiang Gong,Qiye He,Zhixi Su,Rui Liu,Pengfei Zhang
标识
DOI:10.1186/s12967-024-05723-5
摘要
Accurate differentiation between malignant and benign pulmonary nodules, especially those measuring 5-10 mm in diameter, continues to pose a significant diagnostic challenge. This study introduces a novel, precise approach by integrating circulating cell-free DNA (cfDNA) methylation patterns, protein profiling, and computed tomography (CT) imaging features to enhance the classification of pulmonary nodules.
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