抗生素
灭菌(经济)
庆大霉素
材料科学
光催化
纳米技术
环境污染
抗生素耐药性
抗药性
化学
微生物学
环境科学
生物
有机化学
业务
催化作用
环境保护
外汇市场
汇率
财务
作者
Wenmei Han,Wenli Wang,Jie Fan,Runping Jia,Xuchun Yang,Tong Wu,Qingsheng Wu
标识
DOI:10.1016/j.gee.2022.07.004
摘要
The massive use of antibiotics has led to the aggravation of bacterial resistance and also brought environmental pollution problems. This poses a great threat to human health. If the dosage of antibiotics is reduced by increasing its bactericidal performance, the emergence of drug resistance is certainly delayed, so that there's not enough time for developing drug resistance during treatment. Therefore, we selected typical representative materials of metal Ag and semiconductor ZnO nano-bactericides to design and synthesize Ag/ZnO hollow core–shell structures (AZ for short). Antibiotics are grafted on the surface of AZ through rational modification to form a composite sterilization system. The research results show that the antibacterial efficiency of the composite system is significantly increased, from the sum (34.7% + 22.8% = 57.5%) of the antibacterial efficiency of AZ and gentamicin to 80.2%, net synergizes 22.7%, which fully reflects the effect of 1 + 1 > 2. Therefore, the dosage of antibiotics can be drastically reduced in this way, which makes both the possibility of bacterial resistance and medical expenses remarkably decrease. Subsequently, residual antibiotics can be degraded under simple illumination using AZ-self as a photocatalyst, which cuts off the path of environmental pollution. In short, such an innovative route has guiding significance for drug resistance.
科研通智能强力驱动
Strongly Powered by AbleSci AI