生物
微小染色体维持
基因
DNA损伤
遗传学
微小染色体
DNA修复
肿瘤科
癌症研究
内科学
医学
DNA
基因组
真核细胞DNA复制
作者
Shashvat Desai,Michelle A. Wood‐Trageser,Jelena Matic,Jaqueline Chipkin,Huaiyang Jiang,Anne Bachelot,D. Jérôme,Cinzia Sala,Caterina Barbieri,Massimiliano Cocca,Daniela Toniolo,Touraine Philippe,Selma F. Witchel,Aleksandar Rajkovic
摘要
Objective:To assess the frequency of variants, including biallelic pathogenic variants, in minichromosome maintenance 8 (MCM8) and minichromosome maintenance 9 (MCM9), other genes related to MCM8–MCM9, and DNA damage repair (DDR) pathway in participants with primary ovarian insufficiency (POI).
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