医学
组织病理学
软组织
活检
肉瘤
转移
放射科
软组织肉瘤
透明细胞肉瘤
免疫组织化学
病理
癌症
内科学
作者
William Makis,Anthony Ciarallo,Marc Hickeson,Vilma Derbekyan
出处
期刊:Clinical Nuclear Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2011-04-02
卷期号:36 (5): 376-379
被引量:9
标识
DOI:10.1097/rlu.0b013e31820aa28e
摘要
Angiomatoid fibrous histiocytoma is a very rare tumor that accounts for 0.3% of all soft-tissue tumors, and occurs predominantly in the extremities of adolescents and young adults. It has been classified by the World Health Organization as a tumor of uncertain differentiation with intermediate malignant potential, although recent evidence suggests a myoid or myofibroblastic cell origin. Most examples behave in an indolent manner with a regional recurrence rate of 15% and a rate of metastasis of 1%. We present a 29-year-old woman who was referred for an F-18 FDG PET/CT to evaluate a left shoulder mass. She had multiple local FDG-avid lymph nodes, and initial biopsy was suggestive of epithelioid sarcoma. She was treated with chemotherapy, but a post-therapy PET/CT showed minimal response and radical surgical excision was performed. The histopathology and immunohistochemistry was consistent with angiomatoid fibrous histiocytoma. This case highlights a potential new utility for F-18 FDG PET/CT in the staging and evaluation of response to therapy for this very rare soft-tissue tumor.
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