[Interactions of circadian biorhythms of the immune and endocrine systems in mice].

The original and reported data on circadian biorhythms of the immune and endocrine systems are summarized. A hypothetic scheme of the circadian organization of lymphocyte redistribution, proliferation and metabolism in mice is provided, interactions of circadian biorhythms and circadian fluctuations of functional activity of the immune system are demonstrated. It has been shown that circadian rhythms of the immunologic parameters are dependent on the regulative influence of hypophyseal hormones, glucocorticoids, and thymic endocrine factors. Interactions of the immune and endocrine systems in different phases of the circadian cycle have been specified.