摘要
Past, Present and Future of Psychiatry, pp. 295-299 (1994) No AccessWHAT IS SUBSYNDROMAL SYMPTOMATIC DEPRESSION (SSD)?LEWIS L. JUDD, M.D.MARK H. RAPAPORT, M.DMARTIN P. PAULUS, and M.D.JOHN L. BROWNM.SLEWIS L. JUDDDepartment of Psychiatry, University of CA, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0603, USA, MARK H. RAPAPORTDepartment of Psychiatry, University of CA, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0603, USA, MARTIN P. PAULUSDepartment of Psychiatry, University of CA, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0603, USA, and JOHN L. BROWNDepartment of Psychiatry, University of CA, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0603, USAhttps://doi.org/10.1142/9789814440912_0064Cited by:11 PreviousNext AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Library ShareShare onFacebookTwitterLinked InRedditEmail Abstract: We conducted secondary analysis on a subsample of the NIMH Epidemiological Catchment Area Program Database (N = 9160). We found the point prevalence (one month) of one or more depressive symptoms in the general population, excluding respondents with major depression/dysthymia (MD/D), was extremely high at 19.6%. The one-year prevalence of two or more depressive symptoms in the general population, excluding MD/D, was 11.8% (N = 1213). We have labeled this potential clinical condition as Subsyndromal Symptomatic Depression (SSD). The most frequent depressive symptoms reported in SSD are insomnia (40.6%) fatigue (37.8%), recurrent thoughts of death (33.0%), 14-day depressed mood/anhedonia (DSM-111 A criterion) (30.4%), trouble concentrating (22.2%), and significant weight gain (16.2%). SSD sample had many characteristics similar to MD/D, but was distinctly different from the population with no depressive symptoms. Most notably, on variables of negative/adverse outcome, SSD significantly exceeded the no depressive symptoms subsample with higher prevalence of receiving social security benefits, public-assisted disability and lifetime suicide attempts. We found that 27% between these two subsamples of SSD also qualified for DSM-IV Minor Depression. The difference between these two subsamples of SSD is the presence of the DSM-III A Criterion (14 days depressed, sad mood, anhedonia) which is necessary for the diagnosis of Minor Depression. We now propose to redefine SSD as follows: the presence of any two or more depressive symptoms, at least 14 days in duration, excluding individuals who qualify for diagnosis of Minor Depression, Major Depression/Dysthymia. Using this definition, the new SSD subsample has a one-year prevalence of 8.4% in the general population. Approximately 60% of these SSD patients have only two depressive symptoms, the remainder have three or more. SSD, without Minor Depression is associated with increased social disability and dysfunction, including 10.1% lifetime prevalence of suicide attempts — a prevalence level that is 10 times the rate in the general population. SSD is a very intriguing and potentially very important subthreshold form of mood disorder which is deserving of further study and characterization. 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