生物
T细胞受体
封锁
免疫检查点
小细胞肺癌
免疫系统
免疫学
癌
肺
癌症研究
T细胞
免疫疗法
受体
内科学
小细胞癌
医学
遗传学
作者
Peiling Tsou,Chang‐Jiun Wu
标识
DOI:10.1002/eji.202451374
摘要
For each patient in the NSCLC cohort, TCR sequences were converted into numerical vectors using the TCR2Vec model and projected onto a 2D landscape. The aggregated fractions of anti-LAA TEGs per patient were calculated. ICB responders had over-represented anti-LAA TEGs compared to non-responders.
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