间质细胞
玉米赤霉烯酮
氧化磷酸化
芦丁
氧化损伤
信号转导
化学
氧化应激
细胞生物学
细胞凋亡
生物化学
生物
药理学
真菌毒素
抗氧化剂
食品科学
癌症研究
作者
Wang Chenlong,Mengya Wang,Yueru Yang,Chuangjiang Chen,Sajid Ur Rahman,Zhiping Yang,Hongyan Ding,Wanyue Huang,Xichun Wang
标识
DOI:10.1021/acs.jafc.4c09143
摘要
Zearalenone (ZEA) induces oxidative damage in porcine endometrial stromal cells (ESCs), which is a critical factor affecting the growth and reproduction of female pigs. We hypothesize that rutin, a flavonoid antioxidant, can alleviate ZEA-induced cellular damage through the p53 signaling pathway. In this experiment, porcine ESCs were used as a research model. After transfection with siRNA to silence the
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