Optical Coherence Tomography

Normative standards for healthy animal structures have been established by optical coherence tomography (OCT). OCT has been used in animal studies to characterize more precisely ocular lesions, identify the origin of the affected layer, and eventually provide a curative treatment. To acquire a high image resolution, several challenges must be overcome when performing an OCT scan on animals. Sedation or general anesthesia is usually necessary in OCT image acquisition to alleviate motion during image acquisition. Mydriasis, eye position and movements, head position, and corneal hydration must also be managed during the OCT analysis.