Magnetic Delivery of Antigen‐Loaded Magnetic Liposomes for Active Lymph Node Targeting and Enhanced Anti‐Tumor Immunity (Adv. Healthcare Mater. 32/2023)

Vaccine Delivery In article 2301232, Jingyi Sheng, Fang Yang, Ning Gu, and co-workers introduce a magnetic-responsive cancer vaccine, employing antigen-loaded magnetic liposomes (Ag-MLs), for active lymph node targeting. These liposomes, containing mouse melanoma lysate, iron oxide nanoparticles, and CpG adjuvant, display enhanced accumulation in lymph nodes when magnetically guided and demonstrate significant enhancement in anti-tumor immunity in a mouse model. This approach provides potential new avenues for developing effective tumor vaccines.