Wound microenvironment regulatory poly(l-glutamic acid) composite hydrogels containing metal ion-coordinated nanoparticles for effective hemostasis and wound healing

A wound microenvironment regulatory poly( l -glutamic acid) composite hydrogel can promote cell proliferation, migration, and angiogenesis, alleviate inflammation and polarize pro-inflammatory M1 macrophages into pro-healing M2 macrophages, thus accelerating wound healing.