质子疗法
稳健性(进化)
翻译(生物学)
算法
计算机科学
前列腺
医学物理学
医学
放射科
内科学
放射治疗
癌症
生物
信使核糖核酸
生物化学
基因
作者
James Kuan Huei Lee,Kah Seng Lew,Calvin Wei Yang Koh,James Cheow Lei Lee,Andrew A. Bettiol,Sung Yong Park,Hong Qi Tan
摘要
Real-Time Gated Proton Therapy (RGPT) is an active motion management technique that utilizes treatment gating and tumor tracking via fiducial markers. When performing RGPT treatment for prostate cancer, it is essential to account for the CTV displacement relative to the body in the clinical workflow. The workflow at the National Cancer Centre Singapore (NCCS) includes bone matching via CT-CBCT images, followed by fiducial matching via pulsed fluoroscopy (soft tissue matching), and finally, a robustness evaluation procedure to determine if the difference is within an allowable tolerance. In this study, we compare two CTV translation methods for robustness evaluation: (1) an in-house translation algorithm and (2) the RayStation "simulate organ motion" Deformable image registration (DIR) algorithm.
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