Decision regret 3 and 6 months after treatment for head and neck cancer: Observational study of associations with clinicodemographics, anxiety, and quality of life

Abstract Background While quality of life (QOL), psychosocial health, and adverse treatment outcomes have been studied in head and neck cancer (HNC) patients, decision regret is an important and understudied complication that can negatively impact future health care decision making. Methods Data collected using a HNC patient registry with questionnaires administered at initial consultation visits plus 3 and 6 months after treatment completion was retrospectively analyzed. A visual analog anxiety scale and the University of Washington Quality of Life were given at clinic visits. Decision regret was determined using a validated scale. Demographic and clinical variables were collected retrospectively and at baseline. Results Patients with higher anxiety and lower self‐reported QOL had higher concurrent regret at 3‐month ( n = 140) and at 6‐month ( n = 82) post‐treatment. Later disease stage at presentation, nonprimary surgical treatment, and lower health literacy were associated with greater regret. Conclusions Decision regret was highest in HNC patients with high anxiety, low QOL, and more advanced disease.