封锁
癌症研究
免疫检查点
重编程
免疫
生物
医学
肝细胞癌
免疫系统
免疫疗法
免疫学
受体
内科学
细胞
遗传学
作者
Weiqin Yang,Yu Feng,Jingying Zhou,Otto Ka-Wing Cheung,Jian Cao,Jing Wang,Wenshu Tang,Yalin Tu,Liangliang Xu,Feng Wu,Zhiwu Tan,Hanyong Sun,Yuan Tian,John Wong,Paul B.S. Lai,Stephen L. Chan,Anthony W.H. Chan,Patrick Tan,Zhiwei Chen,Joseph J.�Y. Sung
标识
DOI：10.1126/scitranslmed.aaz6804
摘要
HDAC8 inhibition elicits durable responses to immune checkpoint blockade by improving adaptive immune responses through enhancer reprogramming.
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