医学
蛋白尿
肾脏疾病
内科学
盐皮质激素受体
2型糖尿病
糖尿病
疾病
内分泌学
醛固酮
作者
Bertram Pitt,Jingmei Li,Rajiv Agarwal,Stefan D. Anker,George L. Bakris,Peter Rossing,Amer Joseph,Peter Kolkhof,Christina Nowack,Patrick Schloemer,Luís M. Ruilope
标识
DOI:10.1056/nejmoa2110956
摘要
Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, has favorable effects on cardiorenal outcomes in patients with predominantly stage 3 or 4 chronic kidney disease (CKD) with severely elevated albuminuria and type 2 diabetes. The use of finerenone in patients with type 2 diabetes and a wider range of CKD is unclear.
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