Nickel‐Catalyzed Decarboxylative Difluoroalkylation of α,β‐Unsaturated Carboxylic Acids

Abstract The first example of nickel‐catalyzed decarboxylative fluoroalkylation of α,β‐unsaturated carboxylic acids has been developed with commonly available fluoroalkyl halides. This novel transformation has demonstrated broad substrate scope, excellent functional‐group tolerance, mild reaction conditions, and excellent stereoselectivity. Mechanistic investigations indicate that a fluoroalkyl radical is involved in the catalytic cycle.