General Suzuki Coupling of Heteroaryl Bromides by Using Tri-tert-butylphosphine as a Supporting Ligand

Abstract A general procedure for the fast Suzuki coupling of major families of heteroaryl bromides was realized by using Pd(OAc) 2 /P t Bu 3 as the catalyst. Many couplings were finished within minutes at room temperature in n ‐butanol. Different from previous studies, three typical heteroaryl bromides were systematically examined in couplings of various heteroaryl and aryl boronic acids.