In this study, a series of experimental studies was conducted to investigate the fatigue behavior of Ti-6Al-4V alloy at room temperature. Specifically, by inspecting the cylindrical specimens with a circumferential notch of different depths (20-200µm) and notch root radii (20-100µm), the notch effect was systematically investigated with tension-compression fatigue tests (R = –1). To quantify the effects of small notch, the -parameter model was adopted and its applicability for Ti-6Al-4V alloy was examined. Finally, the fatigue characteristics are discussed in conjunction with the behavior of small fatigue cracks at notches.