Optimizing chronic transfusion therapy for survivors of hemoglobin Barts hydrops fetalis

To the editor: Hemoglobin Barts hydrops fetalis (homozygous α-thalassemia) results from deletion of all 4 α-globin genes.[1][1] It was previously considered a universally fatal condition; however, with recent advances in prenatal care and the availability of intrauterine blood transfusions, an