抗氧化剂
化学
超氧化物歧化酶
DPPH
生物化学
食品科学
多糖
高脂血症
丙二醛
脂质过氧化
谷胱甘肽过氧化物酶
过氧化氢酶
马尾松
植物
生物
内分泌学
糖尿病
作者
Lulu Chu,Licong Yang,Lezhen Lin,Jing Wei,Na Wang,Meng Xu,Gaoxiang Qiao,Guodong Zheng
标识
DOI:10.1016/j.ijbiomac.2018.12.082
摘要
The aim of this study is to investigate hypolipidemic and antioxidant effects of Pine needle polysaccharide (PNP) from Pinus massoniana in high-fat diet (HFD)-induced mice. PNP could significantly improve the serum lipid levels (total cholesterol, triacylglycerols, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol), enhance the antioxidant enzymes levels (total antioxidant capability, superoxide dismutase, glutathione peroxidase, catalase), and decrease malondialdehyde (MDA) content in HFD-induced mice. PNP exhibited distinct antioxidant ability on the superoxide anions, 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power (FRAP) in vitro. The average molecular weight (Mw) of PNP was 6.17 × 105 Da, and mainly of fucose, arabinose, galactose, glucose, galacturonic acid. These results suggested that PNP might be used as functional foods and natural drugs in enhancing antioxidant ability and alleviating the hyperlipidemia.
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