Evaluation and comparison of global-feature-based and local-feature-based segmentation algorithms in intracranial visual pathway delineation

Intracranial visual pathway is related to the effective transmission of visual signals to brain. It was not only the target organ of diseases but also the organs at risk in radiotherapy thus its delineation plays an important role in both diagnosis and treatment planning. Traditional manual segmentation method suffered from time- and labor- consuming as well as intra- and inter- variability. In order to overcome these problems, state-of-the-art segmentation models were designed and various features were extracted and utilized, but it's hard to tell their effectiveness on intracranial visual pathway delineation. It's because that these methods worked on different dataset and accompanied with different training tricks. This study aimed to research the contribution of global features and local features in delineating the intracranial visual pathway from MRI scans. The two typical segmentation models, 3D UNet and DeepMedic, were chosen since they focused on global features and local features respectively. We constructed the hybrid model through serially connecting the two mentioned models to validate the performance of combined global and local features. Validation results showed that the hybrid model outperformed the individual ones. It proved that multi scale feature fusion was important in improving the segmentation performance.