Comprehensive geriatric assessment can predict complications in elderly patients after elective surgery for colorectal cancer: A prospective observational cohort study

医学 结直肠癌 前瞻性队列研究 观察研究 队列 择期手术 队列研究 外科 癌症 内科学
作者
Siri Rostoft,Arild Nesbakken,Marit Slaaen,Eva Skovlund,Riccardo A. Audisio,Hans‐Olaf Johannessen,Arne Bakka,Torgeir Bruun Wyller
出处
期刊:Critical Reviews in Oncology Hematology [Elsevier]
卷期号:76 (3): 208-217 被引量:414
标识
DOI:10.1016/j.critrevonc.2009.11.002
摘要

To examine the association between the outcomes of a pre-operative comprehensive geriatric assessment (CGA) and the risk of severe post-operative complications in elderly patients electively operated for colorectal cancer. One hundred seventy-eight consecutive patients ≥70 years electively operated for all stages of colorectal cancer were prospectively examined. A pre-operative CGA was performed, and patients were categorized as fit, intermediate, or frail. The main outcome measure was severe complications within 30 days of surgery. Twenty-one patients (12%) were categorized as fit, 81 (46%) as intermediate, and 76 (43%) as frail. Eighty-three patients experienced severe complications, including three deaths; 7/21 (33%) of fit patients, 29/81 (36%) of intermediate patients and 47/76 (62%) of frail patients (p = 0.002). Increasing age and ASA classification were not associated with complications in this series. CGA can identify frail patients who have a significantly increased risk of severe complications after elective surgery for colorectal cancer.
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