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Dynamically Crosslinked Gold Nanoparticle – Hyaluronan Hydrogels

透明质酸 自愈水凝胶 材料科学 纳米颗粒 明胶 细胞外基质 纳米技术 胶体金 基质(化学分析) 组织工程 计算机科学 生物医学工程 高分子化学 化学 生物化学 解剖 生物 复合材料 医学
作者
Aleksander Skardal,Jianxing Zhang,Lindsi McCoard,Siam Oottamasathien,Glenn D. Prestwich
出处
期刊:Advanced Materials [Wiley]
卷期号:22 (42): 4736-4740 被引量:228
标识
DOI:10.1002/adma.201001436
摘要

Advanced MaterialsVolume 22, Issue 42 p. 4736-4740 Communication Dynamically Crosslinked Gold Nanoparticle – Hyaluronan Hydrogels Aleksander Skardal, Aleksander Skardal Department of Bioengineering, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorJianxing Zhang, Jianxing Zhang Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorLindsi McCoard, Lindsi McCoard Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorSiam Oottamasathien, Siam Oottamasathien Department of Surgery, Division of Pediatric Urology, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorGlenn D. Prestwich, Corresponding Author Glenn D. Prestwich [email protected] Departments of Medicinal Chemistry and Bioengineering, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Departments of Medicinal Chemistry and Bioengineering, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA).Search for more papers by this author Aleksander Skardal, Aleksander Skardal Department of Bioengineering, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorJianxing Zhang, Jianxing Zhang Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorLindsi McCoard, Lindsi McCoard Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorSiam Oottamasathien, Siam Oottamasathien Department of Surgery, Division of Pediatric Urology, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Search for more papers by this authorGlenn D. Prestwich, Corresponding Author Glenn D. Prestwich [email protected] Departments of Medicinal Chemistry and Bioengineering, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA)Departments of Medicinal Chemistry and Bioengineering, Center for Therapeutic Biomaterials, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 (USA).Search for more papers by this author First published: 20 August 2010 https://doi.org/10.1002/adma.201001436Citations: 180Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Bioprinting consists of automated deposition of cells and biomaterials to mimic the architecture of a tissue. Gold nanoparticles act as dynamic, multivalent crosslinkers for thiol-modified hyaluronic acid and gelatin. The resulting synthetic extracellular matrix can be bioprinted into tubular constructs that support cell proliferation and matrix remodeling. The figure shows a view of a tissue construct (containing a fluorescent dye) in the x-y plane, and the inset shows the print head used. Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description adma_201001436_sm_suppl.pdf466.9 KB suppl Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume22, Issue42November 9, 2010Pages 4736-4740 RelatedInformation
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