医学
益生菌
临床试验
疾病
免疫系统
肠道菌群
重症监护医学
健康福利
随机对照试验
免疫学
内科学
生物
传统医学
遗传学
细菌
作者
Mélanie G. Gareau,Philip M. Sherman,W. Allan Walker
标识
DOI:10.1038/nrgastro.2010.117
摘要
The use of probiotics is increasing in popularity for both the prevention and treatment of a variety of diseases. While a growing number of well-conducted, prospective, randomized, controlled, clinical trials are emerging and investigations of underlying mechanisms of action are being undertaken, questions remain with respect to the specific immune and physiological effects of probiotics in health and disease. This Review considers recent advances in clinical trials of probiotics for intestinal disorders in both adult and pediatric populations. An overview of recent in vitro and in vivo research related to potential mechanisms of action of various probiotic formulations is also considered.
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