Regiospecific C2‐Difluoroalkylation on Chromone via Transition‐Metal‐free Oxidative Decarboxylation of Aryldifluoroacetic acids

Abstract A transition‐metal‐free, oxidative decarboxylative reaction of aryldifluoroacetic acids with chromone under mild reaction conditions has been developed. This free‐radical protocol provides an efficient and straightforward access to C 2 ‐difluoroalkylated chromones with excellent regioselectivity in moderate yields to good yields, which are found to be compatible with a broad substrate scope.