医学
胰岛素泵
糖尿病
胰岛素
2型糖尿病
1型糖尿病
闭环
变异系数
门诊部
血糖自我监测
内科学
连续血糖监测
儿科
麻醉
内分泌学
数学
控制工程
工程类
统计
作者
Basilio Pintaudi,Alessandro Nani,Ilaria Gironi,Federico Bertuzzi
出处
期刊:Case Reports
[BMJ]
日期:2022-01-01
卷期号:15 (1): e245336-e245336
标识
DOI:10.1136/bcr-2021-245336
摘要
A 48-year-old deaf-mute man attending our outpatient clinic for long-term severely decompensated type 1 diabetes (mean glycated haemoglobin over 100 mmol/mol) has proved to be the best candidate for the beneficial implant of a next-generation closed loop insulin pump featuring a new refined auto-correction algorithm. The patient had already worn a stand-alone real-time continuous glucose monitoring (rt-CGM) device for 2 years, but his haemoglobin A1c (HbA1c) remained out of target with ample glucose variability. Then, we decided to use a novel advanced hybrid closed-loop insulin pump (the MiniMed 780G) coupled with his CGM device. After only 4 months this system led to a significant improvement in mean daily glucose levels (201±100 mg/dL vs 141±57 mg/dL), time in glucose range (43% vs 78%), percentage of time spent in hyperglycaemia (52% vs 20%), glucose variability (Coefficient of Variation 46% vs 38%), and HbA1c levels (121 mmol/mol vs 56 mmol/mol). The patient was highly satisfied.
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