生物
单核苷酸多态性
SNP公司
疾病
比例危险模型
遗传学
基因
遗传负荷
全基因组关联研究
生存分析
遗传关联
表型
基因型
医学
内科学
人口
环境卫生
近亲繁殖
作者
Xingbin Wang,Oscar L. López,Robert A. Sweet,James T. Becker,Steven T. DeKosky,M. Michael Barmada,Eleanor Feingold,F. Yesim Demirci,M. Ilyas Kamboh
摘要
There is a strong genetic basis for late-onset of Alzheimer's disease (LOAD), and thus far >20 genes/loci have been identified that affect the risk of LOAD. In addition to disease risk, genetic variation at these loci may also affect components of
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