医学
病因学
心肌梗塞
心房颤动
房室传导阻滞
心肌炎
内科学
心肌病
心脏病学
外科
心力衰竭
作者
Jilu Zheng,Xin Chen,Guanhao Luo,Qianhuan Zhang,Hongtao Liao,Hai Deng,Xianhong Fang,Yumei Xue,Yang Liu,Shulin Wu
摘要
Abstract Background Atrioventricular block (AVB) is common in the elderly and therefore considered to be a degenerative disease of the cardiac conduction system. However, there exist other etiologies contributing to AVB in young patients. This study aimed to determine the etiologies in patients aged before 60 years receiving their first pacemaker implantation for AVB in China. Methods and Results Medical records and diagnostic tests of AVB patients were reviewed to identify the etiologies between 2010 and 2021 at Guangdong Provincial People's Hospital. Eight hundred and twenty‐six patients (median age 47 years; 47.9% males) were included. The etiologies were identified in 336 (40.7%) cases, including complications to cardiac surgery ( n = 190 [23.0%]), myocarditis ( n = 57 [6.9%]), myocardial infarction ( n = 25 [3.0%]), complications to catheter‐based interventional procedures ( n = 21 [2.5%]) and others ( n = 43 [5.2%]). AVB caused by myocardial infarction was more common in men (5.8% vs. 0.5%, p < .001), while women received pacing treatment earlier (48 vs. 46 years, p = .019). Men were more likely to suffer from dilated cardiomyopathy (6.6% vs. 2.1%, p = .001) and atrial fibrillation/flutter (23.0% vs. 12.8%, p < .001). The number of first pacemaker implantation increased with age especially among patients with unclear etiologies. Conclusion The etiology of AVB was only determined in approximately 40% of patients receiving their first pacemaker implantation aged before 60 years. The predominance of AVB with unknown etiology and potential gender differences warrants further studies.
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