Two-dimensional semiconducting materials (2D-SCM) have the potential to revolutionize several industries as they appear to be leading the way in terms of innovation. This chapter comprehensively describes 2D-SCM-based logic devices, including logic structure and characteristics, carrier transmission, opportunities, and prospects. 2D-SCM's high carrier mobility, low power consumption, and compatibility with current semiconductor manufacturing techniques are further discussed to illustrate why it is a promising technology. The characteristics of 2D-SCM devices are discussed in depth, including high on/off ratio, minimum subthreshold swing, and high transconductance. The different scattering mechanisms that control carrier transport in 2D-SCM devices, such as phonon scattering, impurity scattering, and surface roughness scattering, and then each mechanism and how it affects carrier mobility and device performance are also discussed. For a comprehensive overview of the technology, the role of defects and disturbances in 2D-SCM devices and their impact on carrier transport are described, as well as the prospects of 2D-SCM logic devices and the potential of 2D-SCM devices in applications such as low-power electronics, high-speed computing, and flexible electronics. Finally, the challenges that must be overcome to remove barriers to production and use of such future 2D-SCM-based logic devices are summarized.