膜
体外膜肺氧合
充氧
杰纳斯
材料科学
化学
纳米技术
麻醉
医学
生物化学
作者
Zhenyi Zhao,Wenqing Gao,Yun Sil Chang,Yue Yang,Hechen Shen,Tong Li,Song Zhao
标识
DOI:10.1002/adhm.202302708
摘要
The oxygenation membrane, a core material of extracorporeal membrane oxygenation (ECMO), is facing challenges in balancing anti-plasma leakage, gas exchange efficiency, and hemocompatibility. Here, inspired by the asymmetric structural features of alveolus pulmonalis, a novel triple-functional membrane for blood oxygenation with a Janus architecture is proposed, which is composed of a hydrophobic polydimethylsiloxane (PDMS) layer to prevent plasma leakage, an ultrathin polyamide layer to enhance gas exchange efficiency with a CO
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