Efficacy of Transabdominal Ultrasound–guided Percutaneous Microwave Ablation in the Treatment of Symptomatic Adenomyosis: A Retrospective Cohort Study

医学 子宫腺肌病 子宫腺肌瘤 子宫肌瘤 可视模拟标度 生活质量(医疗保健) 子宫切除术 回顾性队列研究 微波消融 妇科 经皮 放射科 外科 内科学 子宫内膜异位症 子宫 护理部
作者
Li Shuiping,Zuolin Li,Min Lin,Xiaolian Li,Lei Gao,Jincheng Qiu,Jinghua He,Jiantang Zhang,Guorong Lyu
出处
期刊:Journal of Minimally Invasive Gynecology [Elsevier BV]
卷期号:30 (2): 137-146 被引量:7
标识
DOI:10.1016/j.jmig.2022.11.004
摘要

To evaluate and compare the clinical efficacy of transabdominal ultrasound-guided percutaneous microwave ablation (PMWA) in the treatment of symptomatic focal and nonfocal adenomyosis.Retrospective cohort study.Longyan First Affiliated Hospital of Fujian Medical University.From May 2019 to October 2021, 107 patients with symptomatic adenomyosis who refused hysterectomy received PMWA.Patients were divided into a focal group (n = 47, including 40 focal adenomyosis and 7 adenomyoma cases) and a nonfocal group (n = 60, including 36 diffuse and 24 mixed adenomyosis cases) according to the extent of lesion involvement.We collected and analyzed preoperative baseline data on patient characteristics; postoperative efficacy measures at 3, 6, and 12 months; and intraoperative and postoperative complications. There was a significant post-treatment reduction in the uterine corpus volume and cancer antigen 125 levels, an increase in hemoglobin levels, and an improvement in the Uterine Fibroid Symptom and Health-related Quality of Life scores (consisting of the Symptom Severity Scale and the Health-related Quality of Life scale), dysmenorrhea visual analog scale, and menstrual volume score (MVS) (all p <.05). One patient had recurrence. Most adverse events (72.0%) were mild. Although the nonfocal group had significantly greater anemia severity, higher Symptom Severity Scale and MVS, lower Health-related Quality of Life scale, greater extent and severity of myometrial involvement, and larger uterine corpus volume, after treatment, the uterine corpus volume, uterine corpus reduction rate, cancer antigen 125 levels, hemoglobin levels, Uterine Fibroid Symptom and Health-related Quality of Life score, dysmenorrhea visual analog scale, MVS score, and clinical response rate were similar between the groups (p >.05).PMWA had good, similar, short-term efficacy for symptomatic focal and nonfocal adenomyosis.
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