A biobased magnetic dual-dummy-template molecularly imprinted polymer using a deep eutectic solvent as a coporogen for highly selective enrichment of organophosphates

An eco-friendly magnetic dual-dummy-template molecularly imprinted polymer (MDDMIP) was prepared by a "one-pot" green synthesis using mixed-valence iron hydroxide as the magnetic material, a deep eutectic solvent as the coporogen, and caffeic acid and glutamic acid as binary monomers. The adsorption properties toward organophosphorus pesticides (OPPs) were investigated. High adsorption capacities (269.65–304.93 mg g−1), quick adsorption times (20 s), and high imprinting factors (2.28–3.83) were obtained. The proposed MDDMIP was utilized for magnetic solid phase extraction (MSPE) of OPPs prior to quantification by high performance liquid chromatography (HPLC). The developed method exhibited outstanding linearity (0.05–500 μg L-1), low detection limits (0.003–0.015 μg L-1), and excellent enrichment factors (940–1310 folds). The MSPE-HPLC method was successfully applied for the detection of OPPs in vegetable, fruit, and grain samples with acceptable recoveries (80–119%). This method is a good potential method for the analysis of pesticide residues in complex matrices.