Drug-Induced Hypersensitivity Syndrome With Hemophagocytic Lymphohistiocytosis Related to Piperacillin-Tazobactam: A Case Report

Supplementary Table 1. Result of the RegiSCAR scoring system used to diagnose drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in the patient.a Eosinophils 0.7-1.49× 10 3 /mmc = 1; ≥1.5 × 10 3 /mmc = 2 b ANA, blood culture, serology for HVA/HVB/HVC, Chlamydia/Mycoplasma pneumoniae, other serology/PCR.Nonpositive and ≥ 3 of the above negatives = 1 Legend: Final score < 2: no case, final score 2-3: possible case, final score 4-5: probable case, and final score > 5: definite case Items Yes/No Score Fever ≥ 38.5 °C Yes 1 Enlarged lymph nodes No 0 Eosinophils a Yes 2 Atypical lymphocytes No 0 Skin rash > 50% of body surface area Yes 1 Skin rash suggesting DRESS Yes 1 Skin biopsy suggesting DRESS