Atrial Fibrillation Recurrence in Patients With Transient New-Onset Atrial Fibrillation Detected During Hospitalization for Noncardiac Surgery or Medical Illness

医学 心房颤动 窦性心律 内科学 队列 队列研究 人口 心脏病学 儿科 环境卫生
作者
William F. McIntyre,Maria E. Vadakken,Stuart J. Connolly,Pablo Mendoza,A. Lengyel,Sonia S. Anand,N. Latendresse,Alex Grinvalds,Chinthanie Ramasundarahettige,J. Gabriel Acosta,Kevin J. Um,Jason D. Roberts,David Conen,Jorge Wong,P.J. Devereaux,Emilie P. Belley‐Côté,Richard Whitlock,Jeff S. Healey
出处
期刊:Annals of Internal Medicine [American College of Physicians]
卷期号:176 (10): 1299-1307 被引量:5
标识
DOI:10.7326/m23-1411
摘要

Background: Atrial fibrillation (AF) is often detected for the first time in patients who are hospitalized for another reason. Long-term risks for AF recurrence in these patients are unclear. Objective: To estimate risk for AF recurrence in patients with new-onset AF during a hospitalization for noncardiac surgery or medical illness compared with a matched population without AF. Design: Matched cohort study. (ClinicalTrials.gov: NCT03221777) Setting: Three academic hospitals in Hamilton, Ontario, Canada. Participants: The study enrolled patients hospitalized for noncardiac surgery or medical illness who had transient new-onset AF. For each participant, an age- and sex-matched control participant with no history of AF from the same hospital ward was recruited. All participants left the hospital in sinus rhythm. Measurements: 14-day electrocardiographic (ECG) monitor at 1 and 6 months and telephone assessment at 1, 6, and 12 months. The primary outcome was AF lasting at least 30 seconds on the monitor or captured by ECG 12-lead during routine care at 12 months. Results: Among 139 participants with transient new-onset AF (70 patients with medical illness and 69 surgical patients) and 139 matched control participants, the mean age was 71 years (SD, 10), the mean CHA2DS2-VASc score was 3.0 (SD, 1.5), and 59% were male. The median duration of AF during the index hospitalization was 15.8 hours (IQR, 6.4 to 49.6 hours). After 1 year, recurrent AF was detected in 33.1% (95% CI, 25.3% to 40.9%) of participants in the transient new-onset AF group and 5.0% (CI, 1.4% to 8.7%) of matched control participants; after adjustment for the number of ECG monitors worn and for baseline clinical differences, the adjusted relative risk was 6.6 (CI, 3.2 to 13.7). After exclusion of participants who had electrical or pharmacologic cardioversion during the index hospitalization (n = 40) and their matched control participants and limiting to AF events detected by the patch ECG monitor, recurrent AF was detected in 32.3% (CI, 23.1% to 41.5%) of participants with transient new-onset AF and 3.0% (CI, 0% to 6.4%) of matched control participants. Limitations: Generalizability is limited, and the study was underpowered to evaluate subgroups and clinical predictors. Conclusion: Among patients who have transient new-onset AF during a hospitalization for noncardiac surgery or medical illness, approximately 1 in 3 will have recurrent AF within 1 year. Primary Funding Source: Peer-reviewed grants.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
明月照我程完成签到,获得积分10
1秒前
林虞完成签到,获得积分10
1秒前
脑洞疼应助wwwwwnnnnn采纳,获得10
1秒前
wanci应助噜啦噜啦嘞采纳,获得10
2秒前
无花果应助vuig采纳,获得10
3秒前
wjw完成签到,获得积分10
4秒前
yu_xie发布了新的文献求助10
4秒前
tuanheqi应助九月采纳,获得70
5秒前
很菜的研究生完成签到,获得积分10
6秒前
6秒前
情怀应助缓慢平蓝采纳,获得30
6秒前
7秒前
124yj完成签到,获得积分10
7秒前
完美世界应助zhangjingchang采纳,获得10
7秒前
7秒前
7秒前
唐水之完成签到,获得积分10
8秒前
8秒前
纯纯纯纯完成签到,获得积分10
8秒前
8秒前
害羞行云发布了新的文献求助10
9秒前
知行合一完成签到,获得积分10
10秒前
10秒前
YuuLoon应助海光采纳,获得10
10秒前
外向寄云发布了新的文献求助10
11秒前
11秒前
11秒前
mishen发布了新的文献求助10
11秒前
Wei完成签到 ,获得积分10
13秒前
14秒前
lee发布了新的文献求助10
14秒前
星下梧桐发布了新的文献求助30
14秒前
kiko发布了新的文献求助10
14秒前
15秒前
15秒前
15秒前
QZF发布了新的文献求助10
16秒前
Accept完成签到,获得积分10
16秒前
霸气太英发布了新的文献求助10
16秒前
非也非也6完成签到,获得积分10
17秒前
高分求助中
Evolution 10000
Sustainability in Tides Chemistry 2800
юрские динозавры восточного забайкалья 800
English Wealden Fossils 700
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
A new species of Velataspis (Hemiptera Coccoidea Diaspididae) from tea in Assam 500
Diagnostic immunohistochemistry : theranostic and genomic applications 6th Edition 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3155576
求助须知:如何正确求助?哪些是违规求助? 2806779
关于积分的说明 7870685
捐赠科研通 2465047
什么是DOI,文献DOI怎么找? 1312118
科研通“疑难数据库(出版商)”最低求助积分说明 629877
版权声明 601892